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Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase

Authors :
Ericka Kirkpatrick Roubidoux
Meagan McMahon
Juan Manuel Carreño
Christina Capuano
Kaijun Jiang
Viviana Simon
Harm van Bakel
Patrick Wilson
Florian Krammer
Source :
mSphere, Vol 6, Iss 1 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

The influenza virus neuraminidase is an emerging target for universal influenza virus vaccines. However, in contrast to influenza virus hemagglutinin, we know little about antibody epitopes and antigenic sites on the neuraminidase. Characterizing and defining these sites is aiding vaccine development and helping to understand antigenic drift of NA.

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
23795042
Volume :
6
Issue :
1
Database :
Directory of Open Access Journals
Journal :
mSphere
Publication Type :
Academic Journal
Accession number :
edsdoj.913b78fc146b1872220f8f4b8fdd9
Document Type :
article
Full Text :
https://doi.org/10.1128/mSphere.00958-20