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Biocellulose-based hydrogel dressing as a strategy for the management of chronic arterial wounds
- Source :
- Acta Cirúrgica Brasileira, Vol 39 (2024)
- Publication Year :
- 2024
- Publisher :
- Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2024.
-
Abstract
- ABSTRACT Purpose: To evaluate using a biocellulose-based hydrogel as an adjuvant in the healing process of arterial ulcers. Methods: A prospective single group quasi-experimental study was carried out with chronic lower limb arterial ulcer patients. These patients received biocellulose-based hydrogel dressings and outpatient guidance on dressing and periodic reassessments. The primary outcomes were the ulcer-healing rate and product safety, which were assessed by ulcer area measured in photographic records of pre-treatment and posttreatment after 7, 30, and 60 days. Secondary outcomes were related to clinical assessment by the quality-of-life scores (SF-36 and EQ-5D) and pain, evaluated by the visual analogue scale (VAS). Results: Seventeen participants were included, and one of them was excluded. Six patients (37%) had complete wound healing, and all patients had a significant reduction in the ulcer area during follow-up (233.6mm2 versus 2.7mm2) and reduction on the score PUSH 3.0 (p < 0.0001). The analysis of the SF-36 and EQ-5D questionnaires showed a statistically significant improvement in almost all parameters analyzed and with a reduction of pain assessed by the VAS. Conclusions: The biocellulose-based hydrogel was safe and showed a good perspective to promoting the necessary conditions to facilitate partial or complete healing of chronic arterial ulcers within a 60-day follow-up. Quality of life and pain were positively affected by the treatment.
Details
- Language :
- English
- ISSN :
- 16782674
- Volume :
- 39
- Database :
- Directory of Open Access Journals
- Journal :
- Acta Cirúrgica Brasileira
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9105c03c933b46009446d6783e6d5072
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/acb392924