Back to Search
Start Over
Theranostic Applications of Nanoparticle-Mediated Photoactivated Therapies
- Source :
- Journal of Nanotheranostics, Vol 2, Iss 3, Pp 131-156 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Nanoparticle-mediated light-activated therapies, such as photodynamic therapy and photothermal therapy, are earnestly being viewed as efficient interventional strategies against several cancer types. Theranostics is a key hallmark of cancer nanomedicine since it allows diagnosis and therapy of both primary and metastatic cancer using a single nanoprobe. Advanced in vivo diagnostic imaging using theranostic nanoparticles not only provides precise information about the location of tumor/s but also outlines the narrow time window corresponding to the maximum tumor-specific drug accumulation. Such information plays a critical role in guiding light-activated therapies with high spatio-temporal accuracy. Furthermore, theranostics facilitates monitoring the progression of therapy in real time. Herein, we provide a general review of the application of theranostic nanoparticles for in vivo image-guided light-activated therapy in cancer. The imaging modalities considered here include fluorescence imaging, photoacoustic imaging, thermal imaging, magnetic resonance imaging, X-ray computed tomography, positron emission tomography, and single-photon emission computed tomography. The review concludes with a brief discussion about the broad scope of theranostic light-activated nanomedicine.
Details
- Language :
- English
- ISSN :
- 2624845X
- Volume :
- 2
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Nanotheranostics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.90720c57060a4aa1a1f68be127d51789
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/jnt2030009