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Clinically complete response to abiraterone acetate in a patient with metastatic castration‐resistant prostate cancer

Authors :
Yoshinori Yanai
Takeo Kosaka
Hiroshi Hongo
Mototsugu Oya
Source :
IJU Case Reports, Vol 2, Iss 4, Pp 187-189 (2019)
Publication Year :
2019
Publisher :
Wiley, 2019.

Abstract

Introduction Abiraterone acetate in combination with prednisone is now widely used for the treatment of castration‐resistant prostate cancer. Case presentation A 62‐year‐old patient with a bone metastatic castration‐resistant prostate cancer was started on abiraterone acetate at a dose of 1000 mg a day along with 10 mg prednisone. In spite of castrate testosterone level, the laboratory test showed a relatively high level of serum testosterone, which was 21 ng/dL. Within 6 months, the patient achieved a complete prostate‐specific antigen response. Follow‐up bone scintigraphy demonstrated no area of intense uptake. He had a history of hyperlipidemia and was started on atorvastatin at home just after starting abiraterone acetate. Conclusion This report is a rare case of a clinically complete response to abiraterone acetate in a patient with metastatic castration‐resistant prostate cancer.

Details

Language :
English
ISSN :
2577171X and 16176499
Volume :
2
Issue :
4
Database :
Directory of Open Access Journals
Journal :
IJU Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.9061c1f161764990ab8bb7093bdb606b
Document Type :
article
Full Text :
https://doi.org/10.1002/iju5.12073