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Application of Graph Theory to the elaboration of personal genomic data for genealogical research

Authors :
Vincenzo Palleschi
Luca Pagani
Stefano Pagnotta
Giuseppe Amato
Sergio Tofanelli
Source :
PeerJ Computer Science, Vol 1, p e27 (2015)
Publication Year :
2015
Publisher :
PeerJ Inc., 2015.

Abstract

In this communication a representation of the links between DNA-relatives based on Graph Theory is applied to the analysis of personal genomic data to obtain genealogical information. The method is tested on both simulated and real data and its applicability to the field of genealogical research is discussed. We envisage the proposed approach as a valid tool for a streamlined application to the publicly available data generated by many online personal genomic companies. In this way, anonymized matrices of pairwise genome sharing counts can help to improve the retrieval of genetic relationships between customers who provide explicit consent to the treatment of their data.

Details

Language :
English
ISSN :
23765992
Volume :
1
Database :
Directory of Open Access Journals
Journal :
PeerJ Computer Science
Publication Type :
Academic Journal
Accession number :
edsdoj.8fd36d2fbb7d44ddb55f4958bc077031
Document Type :
article
Full Text :
https://doi.org/10.7717/peerj-cs.27