Fluorescent probes in stomatology

As people pay more and more attention to quality of life, stomatology, as one of the main branches of modern medicine, has experienced rapid development. The research results of many fields, such as molecular biology, analytical chemistry, material chemistry and other disciplines, are gradually applied in the field of stomatology. Due to the advantages of fast response, flexible design, high specificity, high sensitivity and easy operation, fluorescent probe technology is widely used not only in environmental monitoring, food analysis, bioanalysis and life sciences, but also in stomatology as an increasingly powerful analytical and research tool. In this review, we will introduce the uses of fluorescent probes in stomatology for detection, diagnosis, imaging, treatment and screening from five aspects: oral and maxillofacial tumors, dental hard tissue diseases, oral soft tissue diseases, oral related ion diseases, and forensic dentistry. It is hoped that our review may contribute to the further development of fluorescent probes in terms of selectivity, sensitivity, non-toxicity, and stability, thus enhancing the pathogenesis, diagnosis and therapy of stomatological diseases, and laying the foundation for further study of oral disease mechanisms.