Back to Search Start Over

Transcatheter Arterial Embolization (TAE) in the Management of Bleeding in the COVID-19 Patient

Authors :
Roberto Minici
Federico Fontana
Massimo Venturini
Giuseppe Guzzardi
Agostino Siciliano
Filippo Piacentino
Raffaele Serra
Andrea Coppola
Pasquale Guerriero
Biagio Apollonio
Rita Santoro
MGJR Research Team
Luca Brunese
Domenico Laganà
Source :
Medicina, Vol 59, Iss 6, p 1062 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Background and Objectives: Increasing attention is being paid to the coagulation disorders associated with SARS-CoV-2 infection. Bleeding accounts for 3–6% of COVID-19 patient deaths, and is often a forgotten part of the disease. The bleeding risk is enhanced by several factors, including spontaneous heparin-induced thrombocytopenia, thrombocytopenia, the hyperfibrinolytic state, the consumption of coagulation factors, and thromboprophylaxis with anticoagulants. This study aims to assess the efficacy and safety of TAE in the management of bleeding in COVID-19 patients. Materials and Methods: This multicenter retrospective study analyzes data from COVID-19 patients subjected to transcatheter arterial embolization for the management of bleeding from February 2020 to January 2023. Results: Transcatheter arterial embolization was performed in 73 COVID-19 patients for acute non-neurovascular bleeding during the study interval (February 2020–January 2023). Coagulopathy was observed in forty-four (60.3%) patients. The primary cause of bleeding was spontaneous soft tissue hematoma (63%). A 100% technical success rate was recorded; six cases of rebleeding resulted in a 91.8% clinical success rate. No cases of non-target embolization were observed. Complications were recorded in 13 (17.8%) patients. The efficacy and safety endpoints did not differ significantly between the coagulopathy and non-coagulopathy groups. Conclusions: Transcatheter Arterial Embolization (TAE) is an effective, safe and potentially life-saving option for the management of acute non-neurovascular bleeding in COVID-19 patients. This approach is effective and safe even in the subgroup of COVID-19 patients with coagulopathy.

Details

Language :
English
ISSN :
16489144 and 1010660X
Volume :
59
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Medicina
Publication Type :
Academic Journal
Accession number :
edsdoj.8fa41747ea2649a58580cb48bbf08d99
Document Type :
article
Full Text :
https://doi.org/10.3390/medicina59061062