Comfort After Refitting Symptomatic Habitual Reusable Toric Lens Wearers with a New Daily Disposable Contact Lens for Astigmatism

Keith Wan,1 Jay Mashouf,1 Brad Hall2 1Scripps Optometric Group, San Diego, CA, USA; 2Sengi, Penniac, NB, CanadaCorrespondence: Keith Wan, Scripps Optometric Group, 10549 Scripps Poway Pkwy Ste, San Diego, CA, 92131, USA, Tel +1 858-530-2800, Email keithmwan@gmail.comPurpose: To subjectively evaluate comfort with a daily disposable (delefilcon A for astigmatism) contact lens compared to other common weekly/monthly soft toric contact lenses in symptomatic wearers.Methods: This open-label, single arm study enrolled current reusable soft toric lens wearers with minimum score of 12 on the contact lens dry eye (CLDEQ-8) questionnaire. Subjects were also administered the CLDEQ-8 after 1 replacement schedule of their optimized habitual toric lenses (2 to 4 weeks), and after 2 weeks of wear with delefilcon A toric daily disposable lenses (Dailies Total1 for Astigmatism; Alcon Vision LLC, Fort Worth, Texas).Results: A total of 85 subjects completed the study. Mean total CLDEQ-8 score was 16.8 ± 8.1 for subjects refit with their optimized habitual toric lenses and 12.4 ± 7.5 for subjects refit with delefilcon A toric lenses, a difference of 4.3 ± 10.4 (p < 0.001). With delefilcon A toric lenses, 78.9% of subjects reported little to no intensity of eye discomfort, compared to 51.7% for the habitual toric lenses (p = 0.005). In addition, 77.7% of subjects reported little to no intensity of dryness for delefilcon A toric lenses, compared to 50.6% for the habitual toric lenses (p = 0.001).Conclusion: The subjective comfort in symptomatic habitual reusable toric contact lens wearers was improved by refitting with delefilcon A toric lenses.Plain Language Summary: Discomfort while wearing contact lenses is often a reason why patients decide to stop wearing their lenses. There are many different contact lens materials to choose from, and each may affect discomfort differently. The replacement schedule of a contact lens may also be a factor for discomfort, with lenses replaced daily (daily disposables) offering advantages over those replaced weekly or monthly (frequent replacement). The purpose of this study was to subjectively evaluate comfort with a new daily disposable toric contact lens. The results of this study suggest that subjective comfort in symptomatic habitual reusable toric contact lens wearers was improved by refitting with a new daily disposable toric lens.Keywords: comfort, toric, contact lens, delefilcon A, Dailies Total1 for Astigmatism