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MICU1 controls spatial membrane potential gradients and guides Ca2+ fluxes within mitochondrial substructures
- Source :
- Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Within mitochondrial substructures, MICU1 is shown to mediate Ca2+ control over spatial membrane potential gradients (SMPGs), with alterations in SMPGs following Ca2+ binding to MICU1 resulting in spatial cristae depolarization.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 5
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.8ef425fe6be1406f96c6d85f4172f16f
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s42003-022-03606-3