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Hepatoprotective activity of methanolic extract of Malva parviflora against paracetamol-induced hepatotoxicity in mice

Authors :
Tauqeer Hussain Mallhi
Khizar Abbas
Muhammad Ali
Muhammad Imran Qadir
Mohammad Saleem
Yusra Habib Khan
Source :
Bangladesh Journal of Pharmacology, Vol 9, Iss 3 (2014)
Publication Year :
2014
Publisher :
Bangladesh Pharmacological Society, 2014.

Abstract

Malva parviflora (cheeseweed) is traditionally used as hepatoprotective. The current study was conducted to determine its hepatoprotective activity of aqueous methanolic extract of whole plant. Two doses of plant (250 mg/kg and 500 mg/kg) were administered in paracetamol intoxicated mice and results were compared with silymarin. Observational parameters were ALT, AST, ALP and total bilirubin. The results showed that the extract of M. parviflora produced significant (p

Details

Language :
English
ISSN :
19910088
Volume :
9
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Bangladesh Journal of Pharmacology
Publication Type :
Academic Journal
Accession number :
edsdoj.8ebf511962d4ad59d1c5d782c4255eb
Document Type :
article