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New data analysis for BioSAXS at the ESRF

Authors :
Jérôme Kieffer
Martha Brennich
Jean-Baptiste Florial
Marcus Oscarsson
Alejandro De Maria Antolinos
Mark Tully
Petra Pernot
Source :
Journal of Synchrotron Radiation, Vol 29, Iss 5, Pp 1318-1328 (2022)
Publication Year :
2022
Publisher :
International Union of Crystallography, 2022.

Abstract

The second phase of the ESRF upgrade program did not only provide a new storage ring (Extremely Brilliant Source, EBS) but also allowed several beamlines to be refurbished. The BioSAXS beamline (located on port BM29) was upgraded with a new wiggler source and a larger detector. All analysis software has been rewritten to cope with the increased data flux and continues to provide beamline users with reduced and pre-processed data in real time. This article describes FreeSAS, an open-source collection of various small-angle scattering analysis algorithms needed to reduce and analyze BioSAXS data, and Dahu, the tool used to interface data analysis with beamline control. It further presents the data-processing pipelines for the different data acquisitions modes of the beamline, using either a sample changer for individual homogeneous samples or an inline size-exclusion chromatography setup.

Details

Language :
English
ISSN :
16005775
Volume :
29
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Journal of Synchrotron Radiation
Publication Type :
Academic Journal
Accession number :
edsdoj.8e8ef0ebc8b469c94217d5c4bc683b3
Document Type :
article
Full Text :
https://doi.org/10.1107/S1600577522007238