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Tissue engineering for the repair of peripheral nerve injury

Authors :
Pei-Xun Zhang
Na Han
Yu-Hui Kou
Qing-Tang Zhu
Xiao-Lin Liu
Da-Ping Quan
Jian-Guo Chen
Bao-Guo Jiang
Source :
Neural Regeneration Research, Vol 14, Iss 1, Pp 51-58 (2019)
Publication Year :
2019
Publisher :
Wolters Kluwer Medknow Publications, 2019.

Abstract

Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice.

Details

Language :
English
ISSN :
16735374
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Neural Regeneration Research
Publication Type :
Academic Journal
Accession number :
edsdoj.8de79a51b1f44bfdbf45fb770eee667f
Document Type :
article
Full Text :
https://doi.org/10.4103/1673-5374.243701