Back to Search
Start Over
Results of a randomized double-blind multicenter clinical trial of the efficacy and safety of the drug riamilovir for the prevention of COVID-19
- Source :
- Терапевтический архив, Vol 96, Iss 3, Pp 280-285 (2024)
- Publication Year :
- 2024
- Publisher :
- "Consilium Medicum" Publishing house, 2024.
-
Abstract
- Aim. Evaluation of the efficacy and safety of riamilovir as a drug for the prevention of coronavirus infection (COVID-19) in adults who have constant contact with COVID-19 patients as a result of living together. Materials and methods. The study included 750 adult participants living with patients with confirmed polymerase chain reaction method COVID-19, who had a negative polymerase chain reaction result for the SARS-CoV-2 virus at the initial level, met the criteria for inclusion, non-inclusion and exclusion, and signed a voluntary informed consent to participate in a clinical trial. Results. The efficacy, good tolerability and safety of the drug riamilovir for the prevention of COVID-19 infection among people who have come into contact with COVID-19 patients in a family focus of infection have been established. Conclusion. As a result of a multicenter randomized double-blind clinical trial, the effectiveness of the drug riamilovir for the prevention of COVID-19 infection was established. It was shown that the relative risk of disease in the group taking riamilovir for prophylaxis was 88.96% lower than in the control group. Based on the results of a clinical trial, in October 2023 Ministry of Health of the Russian Federation approved the inclusion of a new indication (prophylaxis of COVID-19 infection) in the instructions for the medical use of the drug riamilovir (trade name – Triazavirin®).
- Subjects :
- covid-19
riamilovir
prophylaxis
Medicine
Subjects
Details
- Language :
- Russian
- ISSN :
- 00403660 and 23095342
- Volume :
- 96
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Терапевтический архив
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.8db1998a7524a51b8d3ca2bc93f2cae
- Document Type :
- article
- Full Text :
- https://doi.org/10.26442/00403660.2024.03.202652