A toxin-antidote CRISPR gene drive system for regional population modification

Authors :: Jackson Champer
Esther Lee
Emily Yang
Chen Liu
Andrew G. Clark
Philipp W. Messer
Source :: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Publication Year :: 2020
Publisher :: Nature Portfolio, 2020.
Abstract: CRISPR homing gene drives are highly invasive and can fail due to the rapid evolution of resistance. Here the authors present TARE drive, inspired by naturally occurring selfish genetic elements, which is less vulnerable to resistance and can potentially be confined to a target population.

Full Text Access

Tools