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ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma
- Source :
- Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
- Publication Year :
- 2019
- Publisher :
- Nature Portfolio, 2019.
-
Abstract
- Spiradenoma and cylindroma are skin adnexal tumors that can behave aggressively and undergo malignant transformation. Here, the authors genetically assess a cohort of these adnexal tumours, highlighting recurrent ALPK1 mutations and revealing the genomic landscape of these rare tumours.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 10
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.8cf5f1bae6714e01b43eb450dac4bb01
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-019-09979-0