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A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects

Authors :
Zhaohai Qin
Yumei Xiao
Shijie Du
Xiaoyong Yuan
Dongyan Yang
Chuan Wan
Xiaoqiang Han
Source :
Molecules, Vol 18, Iss 9, Pp 10776-10788 (2013)
Publication Year :
2013
Publisher :
MDPI AG, 2013.

Abstract

A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.

Details

Language :
English
ISSN :
14203049
Volume :
18
Issue :
9
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.8c270f022aee422692f61ccf7f505d64
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules180910776