Normative Data of Macular Thickness Using Spectral Domain Optical Coherence Tomography for Healthy Jordanian Children

Hisham M Jammal,1 Rami Al-Omari,2 Yousef Khader3 1Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Ophthalmology, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 3Department of Public Health, Faculty of Medicine, Jordan University of Science and Technology, Irbid, JordanCorrespondence: Hisham M Jammal, Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, PO Box 1099, Irbid, 21110, Jordan, Tel +962-2-7201000, Fax + 962-2-7095123, Email hmjammal@just.edu.joPurpose: To report normative values of macular thickness and volume by spectral-domain optical coherence tomography (SD-OCT) in the eyes of healthy Jordanian children aged 6– 16 years and assess the correlation of macular parameters with age, sex, and refractive error.Patients and Methods: This observational study included 144 eyes of 144 healthy children. All children underwent comprehensive ocular examination and cycloplegic refraction. Average macular thickness, macular volume, central subfield thickness (CST), and macular thickness for all the Early Treatment Diabetic Retinopathy Study (ETDRS) quadrants were obtained using Primus SD-OCT (Carl Zeiss Meditec).Results: The study group consisted of 68 boys and 76 girls with a mean age (SD) of 10.8 (3.0) years. The mean (SD) spherical equivalent refraction (SER) was 0.56 (1.73) diopters (range: − 4.75 to 4.75). The mean of macular average thickness was 277.2± 12.5 μm, and the mean of the central subfield thickness was 246.7± 16.8 μm. In multivariate analysis, all macular parameters except the central subfield thickness (CST) correlated positively with the SER. Boys had significantly higher CST than girls (p=0.008). None of the macular parameters were correlated with age.Conclusion: Normative data of macular thickness for healthy Jordanian children were established for sex and age groups using SD-OCT.Keywords: central subfield thickness, macular thickness, normative data, pediatric OCT, Primus OCT