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The Relationship of High-Sensitivity C-Reactive Protein (Hs-CRP) Serum Level and Peritonitis in Patients on Peritoneal Dialysis
- Source :
- مجله دانشکده پزشکی اصفهان, Vol 1, Iss 1, Pp 119-123 (2017)
- Publication Year :
- 2017
- Publisher :
- Isfahan University of Medical Sciences, 2017.
-
Abstract
- Background: C-reactive protein (CRP) is a predictor of cardiovascular diseases in both normal people and patients on hemodialysis .This study aimed to assess the relationship of high-sensitivity C-reactive protein (Hs-CRP) serum level and peritonitis in patients on peritoneal dialysis. Methods: 113 patients on peritoneal dialysis in Isfahan city, Iran, participated in our study in 2015. Serum albumin and Hs-CRP levels were measured in each patient at three times (baseline, and 6 and 12 month after that) and the patients were followed up for 1 year. All the patients were evaluated for peritonitis in every visit. At the end of the study, two groups of patients on peritoneal dialysis with and without peritonitis were compared. Findings: Among 113 patients, 24 were excluded from the study because of death or kidney transplantation and 89 patients were included in final analysis. The mean Hs-CRP levels in patients with peritonitis were 4.83, 5.79, and 7.42 mg/l at baseline, and 6 and 12 month after it, respectively; these levels were 4.47, 3.19, and 2.69 mg/l in patients without peritonitis, respectively. In addition, the mean albumin levels in patient with peritonitis were 3.38, 3.29 and 3.40 mg/l at baseline, and 6 and 12 month after it, respectively; these values were 3.56, 4.05, and 3.51 mg/l in patients without peritonitis, respectively. Conclusion: Results showed that with increase in Hs-CRP level, the risk of peritonitis increased. Besides, the albumin level decreased among patients with peritonitis in comparison with patients without peritonitis; there was no significant correlation between albumin level and peritonitis.
Details
- Language :
- Persian
- ISSN :
- 10277595 and 1735854X
- Volume :
- 1
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- مجله دانشکده پزشکی اصفهان
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.8b9cfa250d8b4f6d827fb2beef656eca
- Document Type :
- article