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Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual

Authors :
Young Sam Im
Dae Hoon Yoo
Hyung-Eun Kim
Ji Young Oh
Yong-Ou Kim
Source :
Stem Cell Research, Vol 65, Iss , Pp 102965- (2022)
Publication Year :
2022
Publisher :
Elsevier, 2022.

Abstract

A human induced pluripotent stem cell (hiPSC) line, KSCBi017-A, was generated from a 50-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
18735061
Volume :
65
Issue :
102965-
Database :
Directory of Open Access Journals
Journal :
Stem Cell Research
Publication Type :
Academic Journal
Accession number :
edsdoj.8b462bbed344d24bd6f8e0623a871d6
Document Type :
article
Full Text :
https://doi.org/10.1016/j.scr.2022.102965