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Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’

Authors :
Tatsuro Yoneyama
Kanako Iseki
Masaaki Noji
Hiroshi Imagawa
Toshihiro Hashimoto
Sachiko Kawano
Masaki Baba
Yoshiki Kashiwada
Tadahiro Yahagi
Keiichi Matsuzaki
Akemi Umeyama
Source :
Molecules, Vol 24, Iss 13, p 2504 (2019)
Publication Year :
2019
Publisher :
MDPI AG, 2019.

Abstract

Seven novel norcycloartane glycosides, maryloside A−G (1−7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1−6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity.

Details

Language :
English
ISSN :
14203049
Volume :
24
Issue :
13
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.8a0314c024e242878a0f318217ed75d1
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules24132504