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Relapsing polychondritis (clinical observations)

Authors :
Е. N. Skryabina
О. L. Aleksandrova
I. А. Romanova
А. Р. Rebrov
N. М. Nikitina
Source :
Научно-практическая ревматология, Vol 62, Iss 2, Pp 237-243 (2024)
Publication Year :
2024
Publisher :
IMA PRESS LLC, 2024.

Abstract

Relapsing polychondritis (RPC) is an autoimmune disease manifested by both repeated attacks and a persistent inflammatory process with progressive destruction of cartilaginous structures, in particular, chondritis of the ears, nose, larynx, bronchi, and joints. RPC is a rare disease (about 1000 cases have been described worldwide). Diagnosis of RPC and the choice of treatment tactics are very difficult, which is associated with the rarity of the pathology, undulating, unpredictable course, and the lack of specific laboratory markers.The clinical observations presented in the article confirm the complexity of diagnosing RPC. Before the disease was verified, both patients repeatedly consulted different specialists: the first patient was diagnosed 3 months after the onset of characteristic symptoms of RPC, and the second patient – 1.5 years later. Late diagnosis and the lack of a unified approach to treatment were the reason for the development of prognostically unfavorable lesions in the second patient – chondritis and perichondritis of the larynx.

Details

Language :
Russian
ISSN :
19954484, 19954492, and 09742808
Volume :
62
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Научно-практическая ревматология
Publication Type :
Academic Journal
Accession number :
edsdoj.89cb698e097428081da9e05fcc256bd
Document Type :
article
Full Text :
https://doi.org/10.47360/1995-4484-2024-237-243