Back to Search
Start Over
Solubility and thermodynamic study of deferiprone in propylene glycol and ethanol mixture
- Source :
- BMC Chemistry, Vol 17, Iss 1, Pp 1-10 (2023)
- Publication Year :
- 2023
- Publisher :
- BMC, 2023.
-
Abstract
- Abstract This work aims to obtain the solubility, density and thermodynamic parameters of deferiprone in propylene glycol and ethanol. For this purpose, a shake-flask technique was applied for solid–liquid equilibration and the spectrophotometry method was employed for solubility measurement. Solubility and density of deferiprone in non-aqueous mixtures of propylene glycol and ethanol were measured in the temperatures 293.2–313.2 K. Some equations including van’t Hoff, the Jouyban-Acree, the Jouyban-Acree-van’t Hoff, the mixture response surface and modified Wilson equations were used for the mathematical data modeling. The apparent thermodynamic parameters of the deferiprone dissolution process were computed and reported.
Details
- Language :
- English
- ISSN :
- 2661801X
- Volume :
- 17
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- BMC Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.8939a1ee31314ad4a590b5d02dee2c08
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s13065-023-00950-1