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Experimental Infection of Squirrel Monkeys with Nipah Virus

Authors :
Philippe Marianneau
Vanessa Guillaume
K. Thong Wong
Munisamy Badmanathan
Ren Yih Looi
Séverine Murri
Philippe Loth
Noël Tordo
T. Fabian Wild
Branka Horvat
Hugues Contamin
Source :
Emerging Infectious Diseases, Vol 16, Iss 3, Pp 507-510 (2010)
Publication Year :
2010
Publisher :
Centers for Disease Control and Prevention, 2010.

Abstract

We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys’ suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
16
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.88b9d9538ac24a679aed56b07e57ad2d
Document Type :
article
Full Text :
https://doi.org/10.3201/eid1603.091346