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Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Developmental and regenerative bone formation require the removal of chondrocytes and matrix. Here the authors show that these processes involve mesenchymal stromal cell-derived septoclasts, which disappear after the completion of development but re-emerge during fracture healing.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.87e8bb520b23402b80417daafdf1bb0e
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-28142-w