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IgY Antibodies as Biotherapeutics in Biomedicine

Authors :
Diana León-Núñez
María Fernanda Vizcaíno-López
Magdalena Escorcia
Dolores Correa
Elizabeth Pérez-Hernández
Fernando Gómez-Chávez
Source :
Antibodies, Vol 11, Iss 4, p 62 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

Since the discovery of antibodies by Emil Von Behring and Shibasaburo Kitasato during the 19th century, their potential for use as biotechnological reagents has been exploited in different fields, such as basic and applied research, diagnosis, and the treatment of multiple diseases. Antibodies are relatively easy to obtain from any species with an adaptive immune system, but birds are animals characterized by relatively easy care and maintenance. In addition, the antibodies they produce can be purified from the egg yolk, allowing a system for obtaining them without performing invasive practices, which favors the three “rs” of animal care in experimentation, i.e., replacing, reducing, and refining. In this work, we carry out a brief descriptive review of the most outstanding characteristics of so-called “IgY technology” and the use of IgY antibodies from birds for basic experimentation, diagnosis, and treatment of human beings and animals.

Details

Language :
English
ISSN :
20734468
Volume :
11
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Antibodies
Publication Type :
Academic Journal
Accession number :
edsdoj.87cdd93d80d4120be46bb70cf77d43b
Document Type :
article
Full Text :
https://doi.org/10.3390/antib11040062