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Controlled electroactive release from solid-state conductive elastomer electrodes
- Source :
- Materials Today Bio, Vol 23, Iss , Pp 100883- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- This work highlights the development of a conductive elastomer (CE) based electrophoretic platform that enables the transfer of charged molecules from a solid-state CE electrode directly to targeted tissues. Using an elastomer-based electrode containing poly (3,4-ethylenedioxythiophene) nanowires, controlled electrophoretic delivery of methylene blue (MB) and fluorescein (FLSC) was achieved with applied voltage. Electroactive release of positively charged MB and negatively charged FLSC achieved 33.19 ± 6.47 μg release of MB and 22.36 ± 3.05 μg release of FLSC, a 24 and 20-fold increase in comparison to inhibitory voltages over 1 h. Additionally, selective, and sequential release of the two oppositely charged molecules from a single CE device was demonstrated, showing the potential of this device to be used in multi-drug treatments.
Details
- Language :
- English
- ISSN :
- 25900064
- Volume :
- 23
- Issue :
- 100883-
- Database :
- Directory of Open Access Journals
- Journal :
- Materials Today Bio
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.877ec513699f4c53b6d4a36604ae6aa4
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.mtbio.2023.100883