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A Mendelian randomization study of the effects of blood lipids on breast cancer risk

Authors :
Christoph Nowak
Johan Ärnlöv
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.8742aca1703744a4a49203e403ab0907
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06467-9