Consensus Statement on Proton Therapy for Prostate Cancer

Authors :: Curtis M. Bryant, MD, MPH
Randal H. Henderson, MD, MBA
R. Charles Nichols, MD
William M. Mendenhall, MD
Bradford S. Hoppe, MD, MPH
Carlos E. Vargas, MD
Thomas B. Daniels, MD
C. Richard Choo, MD
Rahul R. Parikh, MD
Huan Giap, MD, PhD
Jerry D. Slater, MD
Neha Vapiwala, MD
William Barrett, MD
Akash Nanda, MD, PhD
Mark V. Mishra, MD
Seungtaek Choi, MD
Jay J. Liao, MD
Nancy P. Mendenhall, MD
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group
Source :: International Journal of Particle Therapy, Vol 8, Iss 2, Pp 1-16 (2021)
Publication Year :: 2021
Publisher :: Elsevier, 2021.
Abstract: Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.