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Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency

Authors :
Megan E. Meuser
Michael B. Murphy
Adel A. Rashad
Simon Cocklin
Source :
Proceedings, Vol 22, Iss 1, p 77 (2019)
Publication Year :
2019
Publisher :
MDPI AG, 2019.

Abstract

The entry of HIV-1 into permissible cells remains an extremely attractive and underexploitedtherapeutic intervention point [...]

Details

Language :
English
ISSN :
25043900 and 20190220
Volume :
22
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Proceedings
Publication Type :
Academic Journal
Accession number :
edsdoj.870c2bc27940483b8668c2517ee5eed0
Document Type :
article
Full Text :
https://doi.org/10.3390/proceedings2019022077