Back to Search Start Over

Role of Circulating Biomarkers in Platinum-Resistant Ovarian Cancer

Authors :
Carolina Maria Sassu
Innocenza Palaia
Serena Maria Boccia
Giuseppe Caruso
Giorgia Perniola
Federica Tomao
Violante Di Donato
Angela Musella
Ludovico Muzii
Source :
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13650 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

Ovarian cancer (OC) is the second most common cause of death in women with gynecological cancer. Considering the poor prognosis, particularly in the case of platinum-resistant (PtR) disease, a huge effort was made to define new biomarkers able to help physicians in approaching and treating these challenging patients. Currently, most data can be obtained from tumor biopsy samples, but this is not always available and implies a surgical procedure. On the other hand, circulating biomarkers are detected with non-invasive methods, although this might require expensive techniques. Given the fervent hope in their value, here we focused on the most studied circulating biomarkers that could play a role in PtR OC.

Details

Language :
English
ISSN :
14220067 and 16616596
Volume :
22
Issue :
24
Database :
Directory of Open Access Journals
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.86fb607e35944b081a46df1397666c5
Document Type :
article
Full Text :
https://doi.org/10.3390/ijms222413650