Evaluation of Acute Kidney Injury in Postcardiotomy Cardiogenic Shock Patients Supported by Extracorporeal Membrane Oxygenation

Background: This study sought to evaluate the incidence of acute kidney injury (AKI) defined by the Kidney Disease: Improving Global Outcomes (KDIGO) group in patients supported by veno-arterial extracorporeal membrane oxygenation (VA ECMO) after post-cardiotomy cardiogenic shock (PCS), and to identify the risk factors for AKI ≥3. Methods: Patients with and without AKI ≥3 were divided into two groups. Potential risk factors for developing AKI ≥3 were evaluated by univariate logistic regression analysis. Patient risk factors (p < 0.1) in the univariate analysis were entered into the multivariable logistic regression model. The tolerance and variance inflation factors (VIF) were calculated to evaluate the collinearity of the potential variables. Results: 136 patients with a mean age of 53.6 ± 13.9 years (66.9% male) were enrolled in the study. 80 patients (58.8%) developed AKI ≥3. Patients with AKI ≥3 required significantly longer mechanical ventilation (200.9 [128.0, 534.8] hours vs. 78.9 [13.0, 233.0] hours, p < 0.001). The ICU stay and hospital stay of patients with AKI ≥3 were much longer than patients with AKI