Lipid profile alterations in non-infectious uveitis: correlation with quantitative optical coherence tomography angiography parameters

Background/aims Lipid profiles have been changed in numerous chronic conditions. The impact of uveitis on lipid metabolism remains unclear.Methods This is a cross-sectional study included 416 patients with non-infectious uveitis (NIU) and 416 healthy subjects. Standard techniques were used to measure total cholesterol (TC), triglycerides (TG), high-density lipoprotein-cholesterol (HDLc), low-density lipoprotein-cholesterol (LDLc) levels. Quantitative optical coherence tomography angiography (OCTA) parameters were obtained from 500 eyes in each group. Correlation analysis examined the relationship between lipid profile and OCTA parameters.Results Patients with NIU exhibited significantly elevated TC, TG and LDLc levels compared with controls (p=0.003; p