Back to Search
Start Over
Dual production of polyhydroxyalkanoates and antibacterial/antiviral gold nanoparticles
- Source :
- Frontiers in Nanotechnology, Vol 5 (2023)
- Publication Year :
- 2023
- Publisher :
- Frontiers Media S.A., 2023.
-
Abstract
- Gold nanoparticles (AuNPs) have been explored for their use in medicine. Here, we report a sustainable, and cost-effective method to produce AuNPs using a bacterial strain such as Pseudomonas mendocina CH50 which is also known to be a polyhydroxyalkanoate (PHA) producer. A cell-free bacterial supernatant, which is typically discarded after PHA extraction, was used to produce spherical AuNPs of 3.5 ± 1.5 nm in size as determined by Transmission Electron Microscopy (TEM) analysis. The AuNPs/PHA composite coating demonstrated antibacterial activity against Staphylococcus aureus 6538P, and antiviral activity, with a 75% reduction in viral infectivity against SARS-CoV-2 pseudotype virus.
Details
- Language :
- English
- ISSN :
- 26733013
- Volume :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Nanotechnology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.868846bdd92144508f8285f4e7ad5298
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fnano.2023.1243056