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Functional crosstalk between the cohesin loader and chromatin remodelers

Authors :
Sofía Muñoz
Andrew Jones
Céline Bouchoux
Tegan Gilmore
Harshil Patel
Frank Uhlmann
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.865112279a4948a1a8847c28f404a2
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-35444-6