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Effectiveness of bronchial thermoplasty in patients with asthma exhibiting overweight/obesity and low quality of life
- Source :
- World Allergy Organization Journal, Vol 16, Iss 3, Pp 100756- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- Bronchial thermoplasty (BT) is effective in some severe asthma patients; however, the specific asthma phenotypes that produce a good response to BT are not fully understood. Clinical data were retrospectively reviewed in severe asthma patients who underwent BT at a single institution in Japan. At the follow-up assessment, the Asthma Quality of Life Questionnaire (AQLQ) scores (P = 0.003), maintenance oral corticosteroid doses (P = 0.027), and exacerbation frequency (P = 0.017) were significantly improved, while prebronchodilator-forced expiratory volume in 1 second (% predicted) did not significantly change (P = 0.19). When we grouped the patients into 2 groups according to their body mass index levels, the AQLQ scores were more improved in patients with overweight/obesity than those with normal weight (P = 0.01). This study showed that patients with non-controlled severe asthma exhibiting overweight/obesity and low quality of life had potential benefits from BT.
Details
- Language :
- English
- ISSN :
- 19394551
- Volume :
- 16
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- World Allergy Organization Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.86326c9916b449ebe772c0dafe6a2d3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.waojou.2023.100756