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A Palladium-Catalyzed 4CzIPN-Mediated Decarboxylative Acylation Reaction of O-Methyl Ketoximes with α-Keto Acids under Visible Light

Authors :
Cheng Wang
Shan Yang
Zhibin Huang
Yingsheng Zhao
Source :
Molecules, Vol 27, Iss 6, p 1980 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

This work presents a palladium-catalyzed oxime ether-directed ortho-selective benzoylation using benzoylformic acid as the acyl source with a palladium catalyst and 4CzIPN as the co-catalyst under light. Various non-symmetric benzophenone derivatives were obtained in moderate to good yields. A preliminary mechanism study revealed that the reaction proceeds through a free radical pathway.

Details

Language :
English
ISSN :
14203049
Volume :
27
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.858a09ab8e8949b98a5866ba4b75941d
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules27061980