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Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area

Authors :
Bryan M. Hooks
Andrew E. Papale
Ronald F. Paletzki
Muhammad W. Feroze
Brian S. Eastwood
Jonathan J. Couey
Johan Winnubst
Jayaram Chandrashekar
Charles R. Gerfen
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.84c613a3ab84486487983e800ed1d0b3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-05780-7