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Efficient allelic-drive in Drosophila

Authors :
Annabel Guichard
Tisha Haque
Marketta Bobik
Xiang-Ru S. Xu
Carissa Klanseck
Raja Babu Singh Kushwah
Mateus Berni
Bhagyashree Kaduskar
Valentino M. Gantz
Ethan Bier
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Gene-drives use CRISPR-Cas9 to be transmitted in a super-Mendelian fashion. Here the authors develop an allelic-drive for selective inheritance of a desired allele.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.84a958ee4384c8680de46671dd3e198
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-09694-w