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Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

Authors :
Eduardo Reátegui
Kristan E. van der Vos
Charles P. Lai
Mahnaz Zeinali
Nadia A. Atai
Berent Aldikacti
Frederick P. Floyd
Aimal H. Khankhel
Vishal Thapar
Fred H. Hochberg
Lecia V. Sequist
Brian V. Nahed
Bob S. Carter
Mehmet Toner
Leonora Balaj
David T. Ting
Xandra O. Breakefield
Shannon L. Stott
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellular vesicles.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.849c53b9683c4d739bdab8480afd929d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-02261-1