Back to Search
Start Over
Health-Related Quality of Life and Frailty in Chronic Liver Diseases
- Source :
- Life, Vol 10, Iss 5, p 76 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- We sought to examine the relationship between frailty and health-related quality of life as evaluated using the 36-item Short-Form Health Survey (SF-36) questionnaire in Japanese chronic liver disease (CLD) patients (n = 341, 122 liver cirrhosis cases, median age = 66 years). Frailty was defined as a clinical syndrome in which three or more of the following criteria were met (frailty score 3, 4, or 5): unintentional body weight loss, self-reported exhaustion, muscle weakness (grip strength: p < 0.0001). In the multivariate analysis, age (p = 0.0126), physical functioning (p = 0.0005), and vitality (p = 0.0246) were independent predictors linked to the presence of frailty. In conclusion, Japanese CLD patients with frailty displayed poorer conditions, both physically and mentally.
- Subjects :
- chronic liver disease
health-related quality of life
SF-36
frailty
Science
Subjects
Details
- Language :
- English
- ISSN :
- 20751729
- Volume :
- 10
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Life
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.844fef499b34802842963256a74272f
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/life10050076