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Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum

Authors :
Felix Evers
Alfredo Cabrera-Orefice
Dei M. Elurbe
Mariska Kea-te Lindert
Sylwia D. Boltryk
Till S. Voss
Martijn A. Huynen
Ulrich Brandt
Taco W. A. Kooij
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Applying complexome profiling, Evers et al. unravel the composition of mitochondrial oxidative phosphorylation complexes in P. falciparum asexual and sexual blood stages. Abundance of these complexes differs between both stages, supporting the hypothesis that a mitochondrial metabolic switch is central to gametocyte development and functioning.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.84175595e535442092eacbb5b96bf88c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23919-x