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Long‐Term Effects of Transcatheter Aortic Valve Implantation on Coronary Hemodynamics in Patients With Concomitant Coronary Artery Disease and Severe Aortic Stenosis

Long‐Term Effects of Transcatheter Aortic Valve Implantation on Coronary Hemodynamics in Patients With Concomitant Coronary Artery Disease and Severe Aortic Stenosis

Authors :
Jeroen Vendrik
Yousif Ahmad
Ashkan Eftekhari
James P. Howard
Gilbert W. M. Wijntjens
Valerie E. Stegehuis
Christopher Cook
Christian J. Terkelsen
Evald H. Christiansen
Karel T. Koch
Jan J. Piek
Sayan Sen
Jan Baan
Source :
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 5 (2020)
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Background As younger patients are being considered for transcatheter aortic valve implantation (TAVI), the assessment and treatment of concomitant coronary artery disease is taking on increased importance. Methods and Results Thirteen contemporary lower‐risk patients with TAVI with severe aortic stenosis (AS) and moderate‐severe coronary lesions were included. Patients underwent assessment of coronary hemodynamics in the presence of severe AS (pre‐TAVI), in the absence of severe AS (immediately post‐TAVI), and at longer‐term follow‐up (6 months post‐TAVI). Fractional flow reserve decreased from 0.85 (0.76–0.88) pre‐TAVI to 0.79 (0.74–0.83) post‐TAVI, and then to 0.71 (0.65–0.77) at 6‐month follow‐up (P

Details

Language :
English
ISSN :
20479980
Volume :
9
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Publication Type :
Academic Journal
Accession number :
edsdoj.8357d10ee44be49f113dc0eea38eb9
Document Type :
article
Full Text :
https://doi.org/10.1161/JAHA.119.015133