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Characterisation of a nucleo-adhesome

Authors :
Adam Byron
Billie G. C. Griffith
Ana Herrero
Alexander E. P. Loftus
Emma S. Koeleman
Linda Kogerman
John C. Dawson
Niamh McGivern
Jayne Culley
Graeme R. Grimes
Bryan Serrels
Alex von Kriegsheim
Valerie G. Brunton
Margaret C. Frame
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Cell adhesion proteins have been described at sites away from the cell surface, including in the nucleus. Here, the authors report the scale of nuclear localisation of adhesion proteins, establishing a nucleo-adhesome and showing that nuclear adhesion proteins can cooperate to control transcription.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.83349dab846e4f55a388ec199c877673
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30556-5