The role of detoxification therapy in fetal growth restriction prevention

The objective of the study was to evaluate the efficacy of detoxification therapy omega-3-polyunsaturated fatty acids and flower pollen (apifitohol) in fetal growth restriction prevention (FGR). In the 1st trimester of pregnancy 140 pregnant women were randomized to receive omega-3-PUFA (group 1), apifitohol (group 2) or no treatment group (group 3). In the beginning of the pregnancy and 1st day after labor all patients passed daily urine Pb/Cd test, and benz(a)pyrene/styrene/formaldehyde blood serum test. The patients of the 1st and 2nd group had much lower level of heavy metals in daily urine and organic pollutants in blood serum after labor compared with the onset of pregnancy. FGR was twice more often, and newborn weight was significantly lower in women of no treatment group ( p=0,0022). Detoxification therapy during the pregnancy can prevent FGR and can be recommended in the condition of environmental pollution.