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Clinical spectrum of COVID-19 at a national referral hospital in western Kenya during the period 2020–2021
- Source :
- Frontiers in Virology, Vol 3 (2023)
- Publication Year :
- 2023
- Publisher :
- Frontiers Media S.A., 2023.
-
Abstract
- IntroductionWe describe the clinical spectrum of COVID-19 cases in western Kenya from 6 April 2020 to 31 May 2021, providing baseline data for further studies into COVID-19 in Kenya.MethodsWe did a retrospective chart review of laboratory and inpatient files of patients diagnosed and managed for COVID-19 at the Moi Teaching and Referral Hospital in Kenya and analyzed the data using Stata® version 16 (StataCorp LP, College Station, TX, USA) and calculated measures of association at 95% CI.ResultsThe patients (n = 1,770) had a mean age of 43 years (SD 20 years) and 55.4% were male. Close to 70% had asymptomatic disease, with the symptomatic cases largely being respiratory in nature. One-quarter had comorbidities. The case fatality rate was 13.6% (n = 240). Male sex increased the odds of mortality by 1.69 (95% CI 1.27–2.25; p ≤ 0.001), and the presence of comorbidities increased the odds of mortality by 3.16 (95% CI 2.38–4.18; p ≤ 0.001). Those aged 59 years and above were 18 times more likely to die from COVID-19 than those below 15 years of age (95% CI 1.61–90.66; p = 0.015).ConclusionCOVID-19 had a significantly high mortality rate in western Kenya. Male sex and the presence of comorbidities increased the risk of severe disease and mortality.
Details
- Language :
- English
- ISSN :
- 2673818X
- Volume :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Virology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.82c9dcdb8934cc38374b7a481dfff2a
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fviro.2023.1202742