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Conformation of the Macrocyclic Drug Lorlatinib in Polar and Nonpolar Environments: A MD Simulation and NMR Study

Authors :
Cheng Peng
Yoseph Atilaw
Jinan Wang
Zhijian Xu
Vasanthanathan Poongavanam
Jiye Shi
Jan Kihlberg
Weiliang Zhu
Máté Erdélyi
Source :
ACS Omega, Vol 4, Iss 26, Pp 22245-22250 (2019)
Publication Year :
2019
Publisher :
American Chemical Society, 2019.

Subjects

Subjects :
Chemistry
QD1-999

Details

Language :
English
ISSN :
24701343
Volume :
4
Issue :
26
Database :
Directory of Open Access Journals
Journal :
ACS Omega
Publication Type :
Academic Journal
Accession number :
edsdoj.8292ad0dedd24a53b3da9ba095d24b07
Document Type :
article
Full Text :
https://doi.org/10.1021/acsomega.9b03797