Association of platelet-to-lymphocyte ratio with the outcomes of peritoneal dialysis-associated peritonitis: a retrospective study

ObjectiveTo explore the correlation between platelet-to-lymphocyte ratio (PLR) and failed treatment in patients with peritoneal dialysis-associated peritonitis (PDAP).MethodsFrom January 2018 to October 2022, 136 hospitalized patients fulfilling the clinical diagnostic criteria of PDAP were selected as study subjects. Demographic profiles, clinical examinations and laboratory parameters were recorded. They were assigned into two groups of successful treatment and failed treatment. General profiles and relevant clinical data of two groups were compared. The relationship between PLR and failed treatment of PDAP was examined by multivariate Logistic regression analysis. And receiver operating characteristic (ROC) curve was plotted for examining the predictive value of PLR on failed treatment of PDAP.ResultsA total of 221 bouts of PDAP occurred in 136 PD patients. As compared with successful treatment group, the levels of PLR[（472 ± 296） vs （232 ± 106）], NLR[（15.40 ± 11.20） vs （7.49 ± 5.92）] and platelet[（256 ± 92）×109/L vs （ 216 ± 84）×109/L] spiked markedly in failed treatment group. There were statistically significant differences (P