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Characteristics, treatment patterns, health care resource utilization and costs in patients with bullous pemphigoid: A retrospective analysis of US health insurance claims dataCapsule Summary

Authors :
Heide A. Stirnadel-Farrant, PhD
Xiao Xu, PhD
Justin Kwiatek, PharmD
Priya Jain, MBBS, MBA
Juliana Meyers, MA
Sean Candrilli, PhD
Daniel Mines, MD, MSCE
Catherine J. Datto, MD, MS
Source :
JAAD International, Vol 13, Iss , Pp 117-125 (2023)
Publication Year :
2023
Publisher :
Elsevier, 2023.

Abstract

Background: Real-world data describing the impact of incident bullous pemphigoid (BP) on patients and health care resource utilization (HCRU) are limited. Objective: To examine characteristics, treatment patterns, HCRU, and costs for incident BP. Methods: Retrospective analysis of 2015 to 2019 US health insurance claims for patients ≥18 years with an incident BP diagnosis. Patients with BP were matched to those without on demographic and clinical characteristics. Statistics were descriptive. Results: The mean Charlson Comorbidity Index score was higher for patients with BP (n = 1108) than without (n = 4621) at baseline (mean [SD]: 3.3 [2.7] vs 2.8 [2.4]) and during follow-up (5.0 [4.9] vs 3.7 [3.0]). Hypertension, diabetes, skin ulcers, chronic pulmonary disease, dyslipidemia, sleep disorders, and congestive heart failure were higher with BP. Most patients with BP received antibiotics (>80%) and/or corticosteroids (>90%). Hospitalizations were more common (44.0% vs 17.1%) and monthly all-cause health care costs more than double ($3214 vs $1353) in patients with BP than without. Limitations: Diagnoses were based on billing codes. HCRU claims data may not reflect the true number of encounters. Conclusion: Incident BP is associated with considerable morbidity, HCRU, and costs. More effective, targeted treatments are needed to improve quality of life, while minimizing exposure to systemic corticosteroids.

Details

Language :
English
ISSN :
26663287
Volume :
13
Issue :
117-125
Database :
Directory of Open Access Journals
Journal :
JAAD International
Publication Type :
Academic Journal
Accession number :
edsdoj.820ee217aef49159733ed8eb45a8acb
Document Type :
article
Full Text :
https://doi.org/10.1016/j.jdin.2023.04.014