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Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

Authors :
Agnieszka Tudek
Paweł S. Krawczyk
Seweryn Mroczek
Rafał Tomecki
Matti Turtola
Katarzyna Matylla-Kulińska
Torben Heick Jensen
Andrzej Dziembowski
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

RNA polyadenosine tails are important for the export, translation and stability of mRNAs and play a role in non-coding RNA biogenesis. Here the authors measure yeast poly(A) tail lengths by direct RNA sequencing, revealing its dynamics in yeast exonuclease, deadenylase and poly(A) polymerase mutants.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.81fd2f0b2b364117add539bf1a1b1ef9
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-25251-w