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Tk-deleted pseudorabies virus retains high pathogenicity in rats

Authors :
Zhang Lirong
Ruan Keyue
Sang Guoju
Xu Zhaoyang
Tong Wu
Yu Hai
Shan Tongling
Gao Fei
Li Liwei
Kong Ning
Tong Guangzhi
Zheng Hao
Source :
Journal of Veterinary Research, Vol 65, Iss 4, Pp 401-405 (2021)
Publication Year :
2021
Publisher :
Sciendo, 2021.

Abstract

The pseudorabies virus (PRV) gene encoding thymidine kinase (tk) is an important virulence-associated factor. Attenuation of PRV in susceptible animals is a frequent result of tk deletion. The aim of the study was to assess the pathogenicity of tk-deleted PRV in rats.

Details

Language :
English
ISSN :
24508608
Volume :
65
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Journal of Veterinary Research
Publication Type :
Academic Journal
Accession number :
edsdoj.81f792cd31fd4f56b78cdbb0f8e86081
Document Type :
article
Full Text :
https://doi.org/10.2478/jvetres-2021-0056